CD28 Antikörper
Kurzübersicht für CD28 Antikörper (ABIN7457969)
Target
Alle CD28 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- Purified
-
Sterilität
- 0.2 μm filtered
-
Endotoxin-Niveau
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
-
Isotyp
- IgG1, kappa
-
-
anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC
anti-CD28 (CD28) antibodyCD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (PE)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (APC)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC
anti-CD28 (CD28) antibody (PerCP)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
Matching Isotype Control: AF/LE Purified Mouse IgG1, κ Isotype Control (ABIN7469767)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 0.5 mg/mL
-
Buffer
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
-
Konservierungsmittel
- Azide free
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Store at 2~8°C. Do not freeze.
-
-
- CD28
-
Andere Bezeichnung
- CD28
-
Hintergrund
- PAS2,MNS,HGpMiX,GYPA,GPSAT,CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
-
Gen-ID
- 940
-
UniProt
- P10747
-
Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
-
