IFNGR1 Antikörper

Produktnummer ABIN7457948

Der Ratte Monoklonal anti-IFNGR1 Antikörper (Klon GR-20) (ABIN7457948) detektiert spezifisch IFNGR1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für IFNGR1 Antikörper (ABIN7457948)

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IFNGR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: GR-20

Produktdetails anti-IFNGR1 Antikörper

Aufreinigung: Purified

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Matching Isotype Control: Purified Rat IgG2a, κ Isotype Control (ABIN7469837)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Andere Bezeichnung: CD119

Hintergrund: Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119,CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Gen-ID: 15979

UniProt: P15261

Pathways: Interferon-gamma Pathway