L-Selectin Antikörper

Produktnummer ABIN7457851

Der Ratte-Monoklonal Anti-L-Selectin-Antikörper wurde für FACS und Neut validiert. Er ist geeignet zum Nachweis von L-Selectin in Proben aus Maus. }

Kurzübersicht für L-Selectin Antikörper (ABIN7457851)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Neutralization (Neut)

Klon: Mel14

Produktdetails anti-L-Selectin Antikörper

Aufreinigung: Purified

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Hintergrund: L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22,CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Gen-ID: 20343

UniProt: P18337