Interleukin 17a Antikörper (PE-Cy7)

Produktnummer ABIN7457646

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Interleukin 17a in ICFC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Interleukin 17a Antikörper (PE-Cy7) (ABIN7457646)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interleukin 17a Antikörper ist konjugiert mit PE-Cy7

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: 17F3

Produktdetails anti-Interleukin 17a Antikörper (PE-Cy7)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: PE/Cyanine7 Mouse IgG1, κ Isotype Control (ABIN7469774)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL-17A

Hintergrund: Interleukin-17A,Il17a,Ctla8,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-41A in vivo.

Gen-ID: 16171

UniProt: Q62386