CD16 Antikörper (PE-Cy5.5)

Produktnummer ABIN7457458

Der Maus Monoklonal Anti-CD16-Antikörper wurde für FACS validiert. Er ist geeignet, CD16 in Proben von Human zu detektieren.

Kurzübersicht für CD16 Antikörper (PE-Cy5.5) (ABIN7457458)

Target: CD16

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD16 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: 3G8

Produktdetails anti-CD16 Antikörper (PE-Cy5.5)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: PE/Cyanine5.5 Mouse IgG1, κ Isotype Control (ABIN7469765)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu CD16

Target: CD16

Andere Bezeichnung: CD16

Hintergrund: FcγRIII,Fc gamma receptor,Fc gamma receptor 3,CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Gen-ID: 941

UniProt: P08637, O75015

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process