CD8 Antikörper (PE-Cy5)

Produktnummer ABIN7457274

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD8 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD8 Antikörper (PE-Cy5) (ABIN7457274)

Target: CD8

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS)

Klon: OKT-8

Produktdetails anti-CD8 Antikörper (PE-Cy5)

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: PE/Cyanine5 Mouse IgG2a, κ Isotype Control (ABIN7469780)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu CD8

Target: CD8

Andere Bezeichnung: CD8

Hintergrund: T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

Gen-ID: 925

UniProt: P01732