ITGA4 Antikörper (PE)

Produktnummer ABIN7457081

Dieses Anti-ITGA4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGA4 in FACS. Geeignet für Human.

Kurzübersicht für ITGA4 Antikörper (PE) (ABIN7457081)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 9F10

Produktdetails anti-ITGA4 Antikörper (PE)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: PE Mouse IgG1, κ Isotype Control (ABIN7469761)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Andere Bezeichnung: CD49d

Hintergrund: Integrin alpha-4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha,CD49d,ITGA4,CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

Gen-ID: 3676

UniProt: P13612

Pathways: Integrin Complex