CCR3 Antikörper (FITC)

Produktnummer ABIN7456929

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CCR3 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCR3 Antikörper (FITC) (ABIN7456929)

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCR3 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: 5E8

Produktdetails anti-CCR3 Antikörper (FITC)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: FITC Mouse IgG2b, κ Isotype Control[MPC-11] (ABIN7469794)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu CCR3

Target: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Andere Bezeichnung: CD193

Hintergrund: CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor,CCR,C-C chemokine receptor type 3,CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

Gen-ID: 1232

UniProt: P51677