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CCR6 Antikörper (FITC)

Dieses Anti-CCR6-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CCR6 in FACS. Geeignet für Human.
Produktnummer ABIN7456841

Kurzübersicht für CCR6 Antikörper (FITC) (ABIN7456841)

Target

Alle CCR6 Antikörper anzeigen
CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reaktivität

  • 72
  • 22
  • 13
  • 3
  • 1
Human

Wirt

  • 47
  • 22
  • 6
  • 3
  • 2
  • 1
Maus

Klonalität

  • 46
  • 32
  • 2
Monoklonal

Konjugat

  • 42
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCR6 Antikörper ist konjugiert mit FITC

Applikation

  • 31
  • 24
  • 22
  • 16
  • 15
  • 7
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

G034E3
  • Isotyp

    IgG2b, kappa
  • Applikationshinweise

    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    Kommentare

    Matching Isotype Control: FITC Mouse IgG2b, κ Isotype Control (ABIN7469794)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.05 % Proclin300, 1 % BSA

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • Target

    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

    Andere Bezeichnung

    CD196/CCR6

    Hintergrund

    CKRL3, CMKBR6, GPR29, STRL22,GPRCY4,CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.

    Gen-ID

    1235

    UniProt

    P51684

    Pathways

    cAMP Metabolic Process
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