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SELPLG Antikörper (Biotin)

SELPLG Reaktivität: Maus FACS Wirt: Ratte Monoclonal 4RA10 Biotin
Produktnummer ABIN7456635
  • Target Alle SELPLG Antikörper anzeigen
    SELPLG (Selectin P Ligand (SELPLG))
    Reaktivität
    • 72
    • 36
    • 19
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 67
    • 24
    • 15
    • 2
    Ratte
    Klonalität
    • 61
    • 42
    • 3
    Monoklonal
    Konjugat
    • 41
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SELPLG Antikörper ist konjugiert mit Biotin
    Applikation
    • 65
    • 60
    • 23
    • 22
    • 16
    • 9
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Klon
    4RA10
    Isotyp
    IgG1, kappa
    Top Product
    Discover our top product SELPLG Primärantikörper
  • Applikationshinweise
    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
    Kommentare

    Matching Isotype Control: Biotin Rat IgG1, κ Isotype Control (ABIN7469820)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300, 1 % BSA
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2~8°C. Do not freeze.
  • Target
    SELPLG (Selectin P Ligand (SELPLG))
    Andere Bezeichnung
    CD162 (SELPLG Produkte)
    Hintergrund
    P-selectin glycoprotein ligand 1,Selplg,PSGL-1,Selectin P ligand,CD162,The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.
    Gen-ID
    20345
    UniProt
    Q62170
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