CD209b Antigen (CD209B) Antikörper (Biotin)

Produktnummer ABIN7456628

Dieses Anti--Antikörper ist ein Armenischer Hamster Monoklonal-Antikörper zur Detektion von in FACS. Geeignet für Maus.

Kurzübersicht für CD209b Antigen (CD209B) Antikörper (Biotin) (ABIN7456628)

Target: CD209b Antigen (CD209B)

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Biotin

Applikation: Flow Cytometry (FACS)

Klon: 22D1

Produktdetails

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Kommentare:

Matching Isotype Control: Biotin Armenian Hamster IgG Isotype Control (ABIN7469874)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Antigendetails

Target: CD209b Antigen (CD209B)

Andere Bezeichnung: CD209b

Hintergrund: CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b,CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Gen-ID: 69165

UniProt: Q8CJ91