CD163 Antikörper (APC)

Produktnummer ABIN7456603

Der Ratte Monoklonal Anti-CD163-Antikörper wurde für FACS validiert. Er ist geeignet, CD163 in Proben von Maus zu detektieren.

Kurzübersicht für CD163 Antikörper (APC) (ABIN7456603)

Target: CD163

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD163 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: S15049F

Produktdetails anti-CD163 Antikörper (APC)

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: APC Rat IgG2a, κ Isotype Control[2A3] (ABIN7469841)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu CD163

Target: CD163

Andere Bezeichnung: CD163

Hintergrund: M130, MM130, SCARI1,CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Gen-ID: 93671

UniProt: Q2VLH6