FOXC1 Antikörper (AA 101-200)

Produktnummer ABIN719291

Der Kaninchen Polyklonal Anti-FOXC1-Antikörper wurde für WB, ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet, FOXC1 in Proben von Human, Maus, Ratte und Ziege zu detektieren.

Kurzübersicht für FOXC1 Antikörper (AA 101-200) (ABIN719291)

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Reaktivität: Human, Maus, Ratte, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-FOXC1 Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Ziege, Human, Maus, Ratte

Homologie: Dog,Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXC1/FREAC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Andere Bezeichnung: FREAC3

Hintergrund:

Synonyms: ARA, FKH L7, FKHL 7, FKHL7, Forkhead Drosophila like 7, Forkhead, forkhead box C1, Forkhead box protein C1,Forkhead drosophila homolog like 7, Forkhead like 7, Forkhead related activator 3, Forkhead related protein FKHL7, Forkhead related transcription factor 3, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FOX C1, FOXC 1, FOXC1, FOXC1_HUMAN, FREAC 3,FREAC-3, FREAC3, homolog-like 7, IGDA, IHG 1, IHG1, IRID 1, IRID1, Iridogoniodysgenesis type 1, Myeloid factor delta.

Background: Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.Involvement in disease, Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3), also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations.

Gen-ID: 2296

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process