HMGN1 Antikörper (AA 90-100)

Produktnummer ABIN7455239

Dieses Anti-HMGN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMGN1 in WB, IF (p), IP und IHC (fp). Geeignet für Human und Maus.

Kurzübersicht für HMGN1 Antikörper (AA 90-100) (ABIN7455239)

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-HMGN1 Antikörper

Bindungsspezifität: AA 90-100

Verwendungszweck: Rabbit anti-HMGN1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 90 and 100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:1,000 - 1:5,000

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu HMGN1

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Andere Bezeichnung: HMGN1

Hintergrund: Background: HMGN1 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA to potentially alter the interaction between the DNA and the histone octamer. The two proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function [taken from NCBI Entrez Gene (GeneID:3150)].

Gen-ID: 3150

NCBI Accession: NP_004956

UniProt: P05114

Pathways: Chromatin Binding