KIF14 Antikörper (C-Term)

Produktnummer ABIN7455214

Der Kaninchen Polyklonal Anti-KIF14-Antikörper wurde für WB, IP, IF/ICC und IHC (fp) validiert. Er ist geeignet, KIF14 in Proben von Human zu detektieren.

Kurzübersicht für KIF14 Antikörper (C-Term) (ABIN7455214)

Target: KIF14 (Kinesin Family Member 14 (KIF14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-KIF14 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-KIF14 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1600 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ICC-IF: 1:200 - 1:1,000. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu KIF14

Target: KIF14 (Kinesin Family Member 14 (KIF14))

Andere Bezeichnung: KIF14

Hintergrund: Background: The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF14 silencing experiments suggest that KIF14 plays a multi-functional role in mitosis and cytokinesis. KIF14 has also been identified as a candidate oncogene whose overexpression may lead to genomic instability and act as a reporter of poor-prognosis in breast cancer.

Gen-ID: 9928

NCBI Accession: NP_055690

UniProt: Q15058