Rekombinanter BRD3 Antikörper (AA 676-726)

Produktnummer ABIN7455203

Dieses Anti-BRD3-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von BRD3 in WB, IP, IF (p), ICC, FACS und IHC (fp). Geeignet für Human.

Kurzübersicht für Rekombinanter BRD3 Antikörper (AA 676-726) (ABIN7455203)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: BLR069G

Produktdetails anti-BRD3 Antikörper

Bindungsspezifität: AA 676-726

Verwendungszweck: Rabbit anti-BRD3 Recombinant Monoclonal Antibody [BLR069G]

Immunogen: between AA 676 and 726

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Andere Bezeichnung: BRD3

Hintergrund: Background: BRD3 (bromodomain containing 3) is a double bromo-domain containing protein. It has been shown to associate with hyperacetylated chromatin of transcribed genes. From this finding it is suggested that BRD3 plays a role in RNA polymerase II transcription through nucleosomes. A chromosomal translocation resulting in a fusion protein involving BRD3 and NUT has been associated with a rare and lethal carcinoma. [taken from the Universal Protein Resource (UniProt) Q15059 and from NCBI Entrez Gene (Gene ID: 8019)].

Gen-ID: 8019

NCBI Accession: NP_031397

UniProt: Q15059

Pathways: Chromatin Binding