Rekombinanter BRD3 Antikörper (AA 676-726)

Produktnummer ABIN7455203

Der Kaninchen Monoklonal anti-BRD3 Antikörper (Klon BLR069G) (ABIN7455203) detektiert spezifisch BRD3 in WB, IHC, IP, IF (p), ICC und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter BRD3 Antikörper (AA 676-726) (ABIN7455203)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: BLR069G

Produktdetails anti-BRD3 Antikörper

Bindungsspezifität: AA 676-726

Verwendungszweck: Rabbit anti-BRD3 Recombinant Monoclonal Antibody [BLR069G]

Aufreinigung: Purified

Immunogen: between AA 676 and 726

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Andere Bezeichnung: BRD3

Hintergrund: BRD3 (bromodomain containing 3) is a double bromo-domain containing protein. It has been shown to associate with hyperacetylated chromatin of transcribed genes. From this finding it is suggested that BRD3 plays a role in RNA polymerase II transcription through nucleosomes. A chromosomal translocation resulting in a fusion protein involving BRD3 and NUT has been associated with a rare and lethal carcinoma. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15059 and from NCBI Entrez Gene (Gene ID: 8019)].

Gen-ID: 8019

UniProt: Q15059

Pathways: Chromatin Binding