LAS1L Antikörper (AA 684-734)
Kurzübersicht für LAS1L Antikörper (AA 684-734) (ABIN7455036)
Target
Alle LAS1L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 684-734
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Verwendungszweck
- Rabbit anti-LAS1L Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 684 and 734
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- LAS1L (LAS1-Like (LAS1L))
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Andere Bezeichnung
- LAS1L
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Hintergrund
- Background: LAS1L is involved in the biogenesis of the 60S ribosomal subunit. It is required for maturation of the 28S rRNA. LAS1L functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes [taken from the Universal Protein Resource (UniProt) Q9Y4W2].
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Gen-ID
- 81887
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NCBI Accession
- NP_112483
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UniProt
- Q9Y4W2
Target
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