FNTA Antikörper (AA 329-379)

Produktnummer ABIN7455017

Dieser Anti-FNTA Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FNTA in WB, IP und IHC (fp). Geeignet für Human.

Kurzübersicht für FNTA Antikörper (AA 329-379) (ABIN7455017)

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-FNTA Antikörper

Bindungsspezifität: AA 329-379

Verwendungszweck: Rabbit anti-FNTA Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 329 and 379

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Andere Bezeichnung: FNTA

Hintergrund: Background: Farnesyl-protein transferase alpha-subunit (FNTA) catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity) [taken from the Universal Protein Resource (UniProt) P49354].

Gen-ID: 2339

NCBI Accession: NP_002018

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling