THO Complex 2 Antikörper (AA 1400-1450)
Kurzübersicht für THO Complex 2 Antikörper (AA 1400-1450) (ABIN7454934)
Target
Alle THO Complex 2 (THOC2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1400-1450
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Verwendungszweck
- Rabbit anti-THOC2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1400 and 1450
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- THO Complex 2 (THOC2)
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Andere Bezeichnung
- THOC2
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Hintergrund
- Background: THO complex subunit 2 (THOC2) is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. THOC2 binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export [taken from the Universal Protein Resource (UniProt) Q8NI27].
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Gen-ID
- 57187
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NCBI Accession
- NP_001075019
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UniProt
- Q8NI27
Target
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