RING1 Antikörper (AA 150-200)

Produktnummer ABIN7454929

Der Kaninchen Polyklonal Anti-RING1-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet, RING1 in Proben von Human zu detektieren.

Kurzübersicht für RING1 Antikörper (AA 150-200) (ABIN7454929)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RING1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-RING1 Antikörper

Bindungsspezifität: AA 150-200

Verwendungszweck: Rabbit anti-RING1 Antibody, Affinity Purified

Homologie: Monkey,Gorilla,Chimpanzee

Aufreinigung: Affinity Purified

Immunogen: between AA 150 and 200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Andere Bezeichnung: RING1

Hintergrund: Background: Ring finger protein 1 (RING1) belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. RING1 can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. RING1 interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It also interacts with the CBX4 protein via its glycine-rich C-terminal domain [taken from NCBI Entrez Gene (Gene ID: 6015)].

Gen-ID: 6015

NCBI Accession: NP_002922

UniProt: Q06587