UBR4 Antikörper (AA 1350-1400)
Kurzübersicht für UBR4 Antikörper (AA 1350-1400) (ABIN7454815)
Target
Alle UBR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1350-1400
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Verwendungszweck
- Rabbit anti-p600 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1350 and 1400
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2-10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
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Andere Bezeichnung
- p600
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Hintergrund
- Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
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Gen-ID
- 23352
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NCBI Accession
- NP_065816
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UniProt
- Q5T4S7
Target
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