NUP50 Antikörper (AA 225-275)

Produktnummer ABIN7454784

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NUP50 in WB, IP und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NUP50 Antikörper (AA 225-275) (ABIN7454784)

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-NUP50 Antikörper

Bindungsspezifität: AA 225-275

Verwendungszweck: Rabbit anti-NUP50 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 225 and 275

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Andere Bezeichnung: NUP50

Hintergrund: Background: The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. There are about 30 different human Nups that have been identified. Nup50 (also called Npap60) appears to not be a fixed structural component of the NPC. Nup50 has been shown to be a component of the importin complex, a protein carrier complex that imports cargo from the cytoplasm to the nucleus through the NPC. In this complex, Nup50 appears to have importance in the late stages of import and functions in complex disassembly and importin recycling.

Gen-ID: 10762

NCBI Accession: NP_009103

UniProt: Q9UKX7

Pathways: Tube Formation