SF3A1 Antikörper (AA 300-350)

Produktnummer ABIN7454762

Produktdetails anti-SF3A1 Antikörper

Target: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Bindungsspezifität: AA 300-350

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-SF3a120/SAP114 Antibody, Affinity Purified

Homologie: Bovine

Aufreinigung: Affinity Purified

Immunogen: between AA 300 and 350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:200 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SF3A1

Target: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Andere Bezeichnung: SF3a120/SAP114 (SF3A1 Produkte)

Synonyme: Dmel\\CG16941 antikoerper, SF3a1 antikoerper, SF3a120 antikoerper, DDBDRAFT_0168938 antikoerper, DDBDRAFT_0233180 antikoerper, DDB_0168938 antikoerper, DDB_0233180 antikoerper, 1200014H24Rik antikoerper, 5930416L09Rik antikoerper, AI159724 antikoerper, si:dz150f13.2 antikoerper, wu:fc38e01 antikoerper, wu:fc50a11 antikoerper, wu:fj37c05 antikoerper, zgc:65786 antikoerper, PRP21 antikoerper, PRPF21 antikoerper, SAP114 antikoerper, SF3A120 antikoerper, CG16941 gene product from transcript CG16941-RA antikoerper, SWAP/Surp domain-containing protein antikoerper, splicing factor 3a, subunit 1 antikoerper, splicing factor 3a subunit 1 antikoerper, CG16941 antikoerper, sf3a1 antikoerper, spl1 antikoerper, Sf3a1 antikoerper, SF3A1 antikoerper

Hintergrund: Background: SF3a120/SAP114 is a 120 kDa subunit of the heterotrimeric splicing factor 3a (SF3A) protein complex. SF3A along with SF3B and a 12S RNA subunit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. SF3a120/SAP114 bears two SURP motif repeats and one ubiquitin-like domain. SURP motifs are found among proteins involved in regulated mRNA splicing. The SURP motifs along with the ubiquitin-like domain of SF3a120/SAP114 appear to function in the heterotrimeric formation between the 120, 60 and 66 kDa subunits.

Gen-ID: 10291

NCBI Accession: NP_005868

UniProt: Q15459

Pathways: Ribonucleoprotein Complex Subunit Organization