SF3A1 Antikörper (AA 300-350)

Produktnummer ABIN7454762

Dieses Anti-SF3A1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SF3A1 in WB, IP und IHC (fp). Geeignet für Human und Maus.

Kurzübersicht für SF3A1 Antikörper (AA 300-350) (ABIN7454762)

Target: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-SF3A1 Antikörper

Bindungsspezifität: AA 300-350

Verwendungszweck: Rabbit anti-SF3a120/SAP114 Antibody, Affinity Purified

Homologie: Bovine

Aufreinigung: Affinity Purified

Immunogen: between AA 300 and 350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:200 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SF3A1

Target: SF3A1 (Splicing Factor 3a, Subunit 1 (SF3A1))

Andere Bezeichnung: SF3a120/SAP114

Hintergrund: Background: SF3a120/SAP114 is a 120 kDa subunit of the heterotrimeric splicing factor 3a (SF3A) protein complex. SF3A along with SF3B and a 12S RNA subunit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. SF3a120/SAP114 bears two SURP motif repeats and one ubiquitin-like domain. SURP motifs are found among proteins involved in regulated mRNA splicing. The SURP motifs along with the ubiquitin-like domain of SF3a120/SAP114 appear to function in the heterotrimeric formation between the 120, 60 and 66 kDa subunits.

Gen-ID: 10291

NCBI Accession: NP_005868

UniProt: Q15459

Pathways: Ribonucleoprotein Complex Subunit Organization