CDT2/RAMP Antikörper (C-Term)

Produktnummer ABIN7454696

Produktdetails anti-CDT2/RAMP Antikörper

Target: CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDT2/RAMP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-DTL/CDT2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 680 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CDT2/RAMP

Target: CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))

Andere Bezeichnung: DTL/CDT2 (DTL Produkte)

Synonyme: CDT2 antikoerper, DCAF2 antikoerper, L2DTL antikoerper, RAMP antikoerper, 2810047L02Rik antikoerper, 5730564G15Rik antikoerper, Ramp antikoerper, RGD1310439 antikoerper, cdt2 antikoerper, cdt2-a antikoerper, dcaf2 antikoerper, l2dtl antikoerper, ramp antikoerper, cb151 antikoerper, chunp6871 antikoerper, wu:fb54b02 antikoerper, denticleless E3 ubiquitin protein ligase homolog antikoerper, denticleless E3 ubiquitin protein ligase antikoerper, denticleless E3 ubiquitin protein ligase homolog S homeolog antikoerper, denticleless E3 ubiquitin protein ligase homolog (Drosophila) antikoerper, DTL antikoerper, Dtl antikoerper, dtl.S antikoerper, dtl antikoerper

Hintergrund: Background: DTL/CDT2 is a component of the CUL4A-DDB1 E3 ubiquitinating complex and plays a role in downregulating CDT1, an essential component of pre-replication complexes (Pre-RC) that ensures the genome is replicated only once per cycle. As part of the CUL4A-DDB1 E3 ligase complex DTL/CDT2 is also involved in the regulation of other proteins involved in the G2/M cell cycle checkpoint.

Gen-ID: 51514

NCBI Accession: NP_057532

UniProt: Q9NZJ0