PARP10 Antikörper (AA 300-350)

Produktnummer ABIN7454656

Der Kaninchen-Polyklonal Anti-PARP10-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet zum Nachweis von PARP10 in Proben aus Human. }

Kurzübersicht für PARP10 Antikörper (AA 300-350) (ABIN7454656)

Target: PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-PARP10 Antikörper

Bindungsspezifität: AA 300-350

Verwendungszweck: Rabbit anti-PARP10 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 300 and 350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000: 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PARP10

Target: PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))

Andere Bezeichnung: PARP10

Hintergrund: Background: PARP10 is a member of the poly(ADP-ribose) polymerase (PARP) family involved in a variety of processes which includes DNA metabolism, the DNA damage response, transcription and the maintenance of genomic stability. Although each member of the PARP family exhibits poly(ADP-ribose) polymerase activity which catalyzes the attachment of ADP-ribose units from NAD+ to substrate proteins, the endogenous substrates of many of the family members, including PARP10, remain to be identified. Recent studies have shown that PARP10 is localized to the nucleoli and associates with RNA polymerase II. PARP10 is a substrate of and is activated by CDK2 and may serve an important function in cell proliferation.

Gen-ID: 84875

NCBI Accession: NP_116178

UniProt: Q53GL7