INPPL1 Antikörper (AA 100-150)
Kurzübersicht für INPPL1 Antikörper (AA 100-150) (ABIN7454647)
Target
Alle INPPL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 100-150
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Verwendungszweck
- Rabbit anti-INPPL1/SHIP2 Antibody, Affinity Purified
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Homologie
- Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 100 and 150
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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Andere Bezeichnung
- INPPL1/SHIP2
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Hintergrund
- Background: INPPL1 (Inositol Polyphosphate Phosphatase-Like Protein 1) is a phosphatidylinositol phosphatase that negatively regulates phosphoinositide 3-kinase (PI3K) pathways related to numerous cell activities. INPPL1 plays a role in PI3K-dependent insulin, macrophage colony-stimulating factor, and EGF signaling. INPPL1 is also involved in actin cytoskeletal remodeling, actin dynamics, and neuritogenesis. INPPL1 interacts with SHC1 (src-homology domain) to mediate EGFR signaling.
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Gen-ID
- 3636
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NCBI Accession
- NP_001558
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UniProt
- O15357
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Pathways
- Platelet-derived growth Factor Receptor Signaling
Target
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