CBP Antikörper (AA 2375-2425)

Produktnummer ABIN7454618

Dieses Anti-CBP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CBP in WB, IP und IHC (fp). Geeignet für Human.

Kurzübersicht für CBP Antikörper (AA 2375-2425) (ABIN7454618)

Target: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-CBP Antikörper

Bindungsspezifität: AA 2375-2425

Verwendungszweck: Rabbit anti-CBP Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 2375 and 2425

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 1 - 4 μg/mg lysate

WB: 1:1,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CBP

Target: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Andere Bezeichnung: CBP

Hintergrund: Background: CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.

Gen-ID: 1387

NCBI Accession: NP_004371

UniProt: Q92793

Pathways: T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha