NCOA2 Antikörper (C-Term)

Produktnummer ABIN7454615

Der Kaninchen Polyklonal anti-NCOA2 Antikörper (ABIN7454615) detektiert spezifisch NCOA2 in WB, IP und IHC (fp). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für NCOA2 Antikörper (C-Term) (ABIN7454615)

Target: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-NCOA2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-NCOA2/SRC2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1400 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 1 - 4 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NCOA2

Target: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Andere Bezeichnung: NCOA2/SRC2

Hintergrund: Background: Nuclear Receptor Coactivator 2 (NCOA2) is a member of the p160 family of nuclear receptor coactivators that also includes steroid receptor coactivator-1 (SRC-1) and p300/CBP-interacting protein (p/CIP). As Coactivators, this group of proteins helps recruit acetyltransferases and methyltransferases such as p300/CBP and CARM1 to facilitate chromatin remodeling and transcription factor recruitment, and to enhance gene expression. NCOA2 has been demonstrated to be important for the control of energy balance between white and brown adipose tissue.

Gen-ID: 10499

NCBI Accession: NP_006531

UniProt: Q15596

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling