NMNAT1 Antikörper (AA 229-279)
Kurzübersicht für NMNAT1 Antikörper (AA 229-279) (ABIN7454578)
Target
Alle NMNAT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 229-279
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Verwendungszweck
- Rabbit anti-NMNAT1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 229 and 279
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
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Andere Bezeichnung
- NMNAT1
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Hintergrund
- Background: Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. NMNAT1 is an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. NMNAT1 is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown NMNAT1 can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecul [taken from NCBI Entrez Gene (Gene ID: 64802)].
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Gen-ID
- 64802
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NCBI Accession
- NP_073624
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UniProt
- Q9HAN9
Target
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