FKBP4 Antikörper (AA 1-50)
Kurzübersicht für FKBP4 Antikörper (AA 1-50) (ABIN7454535)
Target
Alle FKBP4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-FKBP4/FKBP52 Antibody, Affinity Purified
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Homologie
- Rat,Bovine,Rabbit
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1 and 50
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended. Use rabbit anti-FKBP4/FKBP52 antibody A301-427A.
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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Andere Bezeichnung
- FKBP4/FKBP52
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Hintergrund
- Background: FKBP4/FKBP52 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP52 exhibits peptidyl-prolyl cis-trans isomerase activity, but does not appear to mediate the immunosuppressive activities of FK506. The most studied role of FKBP4/FKBP52 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperone Hsp90, FKBP4/FKBP52 is able to influence steroid-hormone binding affinity and transcriptional activity.
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Gen-ID
- 2288
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NCBI Accession
- NP_002005
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UniProt
- Q02790
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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