LUC7-Like 3 Antikörper (AA 1-50)

Produktnummer ABIN7454406

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LUC7-Like 3 in IP und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LUC7-Like 3 Antikörper (AA 1-50) (ABIN7454406)

Target: LUC7-Like 3 (LUC7L3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LUC7-Like 3 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-LUC7-Like 3 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-CROP/Luc7A Antibody, Affinity Purified

Homologie: Mouse,Bovine,Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. A301-498A has not performed satisfactorily when used for WB of CROP/Luc7A in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of CROP/Luc7A.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu LUC7-Like 3

Target: LUC7-Like 3 (LUC7L3)

Andere Bezeichnung: CROP/Luc7A

Hintergrund: Background: Cisplatin resistance-associated overexpressed protein (CROP) was originally cloned by differential display from cisplatin-resistant cells. It is an SR-related protein and the human homolog of the yeast protein, Luc7p. Luc7p is an essential protein involved in vegetative growth and 5'-splice recognition. CROP/Luc7a contains arginine- and glutamate-rich domains (RE domains) and arginine- and serine-rich domains (RS domains). It localizes to the nucleus and is distributed as speckles. CROP/Luc7a has been shown to interact with SF2/ASF, a protein involved in RNA splicing. Due to this association and the known function of its yeast homolog, CROP/Luc7a is proposed to play a role in RNA splicing.

Gen-ID: 51747

NCBI Accession: NP_057508

UniProt: O95232

Pathways: Ribonucleoprotein Complex Subunit Organization