CHD3 Antikörper (AA 1950-2000)

Produktnummer ABIN7454393

Dieses Anti-CHD3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHD3 in IP und IHC (fp). Geeignet für Human und Maus.

Kurzübersicht für CHD3 Antikörper (AA 1950-2000) (ABIN7454393)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD3 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-CHD3 Antikörper

Bindungsspezifität: AA 1950-2000

Verwendungszweck: Rabbit anti-CHD3 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1950 and 2000

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-CHD3 antibody A301-219A.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CHD3

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Andere Bezeichnung: CHD3

Hintergrund: Background: CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.

Gen-ID: 1107

NCBI Accession: NP_001005273

UniProt: Q12873