CDT2/RAMP Antikörper (AA 375-425)
Kurzübersicht für CDT2/RAMP Antikörper (AA 375-425) (ABIN7454381)
Target
Alle CDT2/RAMP (DTL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 375-425
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Verwendungszweck
- Rabbit anti-DTL/CDT2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 375 and 425
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-DTL/CDT2 antibody A300-948A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))
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Andere Bezeichnung
- DTL/CDT2
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Hintergrund
- Background: DTL/CDT2 is a component of the CUL4A-DDB1 E3 ubiquitinating complex and plays a role in downregulating CDT1, an essential component of pre-replication complexes (Pre-RC) that ensures the genome is replicated only once per cycle. As part of the CUL4A-DDB1 E3 ligase complex DTL/CDT2 is also involved in the regulation of other proteins involved in the G2/M cell cycle checkpoint.
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Gen-ID
- 51514
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NCBI Accession
- NP_057532
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UniProt
- Q9NZJ0
Target
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