Apo(a) Antikörper

Produktnummer ABIN7454045

Der Ziege Polyklonal anti-Apo(a) Antikörper (Klon A03) (ABIN7454045) detektiert spezifisch Apo(a) in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Apo(a) Antikörper (ABIN7454045)

Target: Apo(a) (apo(a)) (Apolipoprotein A (apo(a)))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Apo(a) Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: A03

Produktdetails anti-Apo(a) Antikörper

Verwendungszweck: Goat anti-Human ApoAI Antibody Affinity Purified

Aufreinigung: Antigen Affinity Purified

Immunogen: Human Apolipoprotein (a)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02 % Sodium azide, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu Apo(a)

Target: Apo(a) (apo(a)) (Apolipoprotein A (apo(a)))

Andere Bezeichnung: Apo(a)

Hintergrund: Apo AI comprises approximately 70 % of the protein moiety in HDL. It is a single polypeptide chain consisting of 243 amino acid residues without disulfide bound and with glutamic acid as the C-terminal residue and aspartic acid as the N-terminal residue. The molecular weight is reported to be 28 kDa (Brewer et al., 1978). The roles of Apo AI in HDL function include reverse cholesterol transportation, lipid cholesterol binding, lecithin-cholesterol acyl transferase (LCAT) activation, and receptor binding, which is responsible for cholesterol esterification in plasma. Besides participate in cholesterol metabolism, Apo AI and HDL also suppress neutrophil activation, inhibit bacterial endotoxin, induce trypanosomal lysis, and other physiological activities. (Brouillette et al., 2001). Apo AI levels may be inversely related to the risk of coronary disease. In previous research, Apo AI may affect diet-induced inflammation by either directly or indirectly altering lipid rafts. (Cheng et al., 2012)

Gen-ID: 335

UniProt: P02647