Rekombinanter ZEB2 Antikörper (AA 1164-1214)
Kurzübersicht für Rekombinanter ZEB2 Antikörper (AA 1164-1214) (ABIN7453993)
Target
Alle ZEB2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1164-1214
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Verwendungszweck
- Rabbit anti-ZEB2/SIP Recombinant Monoclonal Antibody [BLR115H]
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Immunogen
- between AA 1164 and 1214 (C-term)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))
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Andere Bezeichnung
- ZEB2/SIP
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Hintergrund
- Background: Smad interacting protein 1 (SIP1) is a transcriptional inhibitor that binds to the DNA sequence, 5'-CACCT-3', in different promoters. SIP1 has been shown to repress the transcription of E-cadherin. Defects in the gene which encodes for SIP1, ZEB2, are the cause of Hirschsprung disease-mental retardation syndrome (Hirschsprung disease) also known as Mowat-Wilson syndrome (MWS). Hirschsprung disease is a rare autosomal dominant complex developmental disorder [taken from the Universal Protein Resource (UniProt) O60315].
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Gen-ID
- 9839
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NCBI Accession
- NP_055610
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UniProt
- O60315
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Pathways
- Tube Formation
Target
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