Rekombinanter MED12 Antikörper (AA 2127-2177)

Produktnummer ABIN7453977

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch MED12 in IHC, WB, IP und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Rekombinanter MED12 Antikörper (AA 2127-2177) (ABIN7453977)

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MED12 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: BLR084G

Produktdetails anti-MED12 Antikörper

Bindungsspezifität: AA 2127-2177

Verwendungszweck: Rabbit anti-MED12 Recombinant Monoclonal Antibody [BLR084G]

Immunogen: between AA 2127 and 2177 (C-term)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MED12

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Andere Bezeichnung: MED12

Hintergrund: Background: MED12 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. In this context, MED12 interaction with beta-catenin has been shown to be required for Wnt-signaling dependent transcription.

Gen-ID: 9968

NCBI Accession: NP_005111

UniProt: Q93074

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation