Rekombinanter FGL1 Antikörper (AA 18-312)
Kurzübersicht für Rekombinanter FGL1 Antikörper (AA 18-312) (ABIN7453972)
Target
Alle FGL1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 18-312
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Verwendungszweck
- Rabbit anti-Hepassocin/FGL1 Recombinant Monoclonal Antibody [BLR210K] - BSA-Free
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Aufreinigung
- Purified
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Immunogen
- residues 18-312 (full length)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- FGL1 (Fibrinogen-Like 1 (FGL1))
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Andere Bezeichnung
- Hepassocin/FGL1
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Hintergrund
- Hepassocin, also known as Fibrinogen-like 1 (FGL1), is a member of the fibrinogen family whose members share a fibrinogen domain at their C-termini. However, it lacks the platelet-binding site, cross-linking region and thrombin-sensitive site which are necessary for fibrin clot formation. Hepassocin/FGL1 is secreted by hepatocytes and may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is an immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 [taken from NCBI Entrez Gene (Gene ID: 2267)].
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Gen-ID
- 2267
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UniProt
- Q08830
Target
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