Rekombinanter Claudin 1 Antikörper (C-Term)

Produktnummer ABIN7453966

Der Kaninchen Monoklonal Anti-Claudin 1-Antikörper wurde für WB, IHC, IP und ICC validiert. Er ist geeignet, Claudin 1 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter Claudin 1 Antikörper (C-Term) (ABIN7453966)

Target: Claudin 1 (CLDN1)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: BLR094G

Produktdetails anti-Claudin 1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-Claudin-1 Recombinant Monoclonal Antibody [BLR094G]

Immunogen: between AA 161 and and 211 (C-term)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: Claudin-1

Hintergrund: Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. Claudin-1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [taken from the Universal Protein Resource (UniProt) O95832].

Gen-ID: 9076

NCBI Accession: NP_066924

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C