BANP Antikörper (C-Term)

Produktnummer ABIN7453906

Der Kaninchen Polyklonal Anti-BANP-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet, BANP in Proben von Human und Maus zu detektieren.

Kurzübersicht für BANP Antikörper (C-Term) (ABIN7453906)

Target: BANP (Protein BANP (BANP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BANP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-BANP Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-SMAR1/BANP Antibody, Affinity Purified

Homologie: Bovine

Aufreinigung: Affinity Purified

Immunogen: between AA 425 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 1:500 - 1:2,500

WB: 1:10,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BANP

Target: BANP (Protein BANP (BANP))

Andere Bezeichnung: SMAR1/BANP

Hintergrund: Background: SMAR1/BANP was identified as a protein that binds the scaffold/matrix associated region of the T-cell receptor beta locus (SMAR1) and as a protein that interacts with BTG3, a member of structurally related proteins that regulate cell proliferation (BANP- BTG-associated nuclear protein). SMAR1/BANP is a DNA binding protein that is reported to be a tumor suppressor and transcriptional repressor. SMAR1/BANP can down-regulate cyclin D1 transcription by binding to the cyclin D1 promoter and through its interaction with HDAC1 (histone deacetylase 1). SMAR1 has also been shown to interact with p53 and modulate its activity.

Gen-ID: 54971

UniProt: Q8N9N5, Q96GJ7