BUB1B Antikörper (AA 1-50)

Produktnummer ABIN7453860

Der Kaninchen Polyklonal anti-BUB1B Antikörper (ABIN7453860) detektiert spezifisch BUB1B in WB, IP und IHC (fp). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BUB1B Antikörper (AA 1-50) (ABIN7453860)

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BUB1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-BUB1B Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-BubR1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BUB1B

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Andere Bezeichnung: BubR1

Hintergrund: Background: BubR1 is cell cycle checkpoint kinase and component of the spindle checkpoint machinery. BubR1 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. BubR1 is part of the mitotic checkpoint complex that also includes Bub3, Mad2, and Cdc20. In this trimer BubR1 functions to inhibit the anaphase promoting complex (APC) that promotes chromosome segregation. BubR1 is suggested to be a paralog of Bub1.

Gen-ID: 701

NCBI Accession: NP_001202

UniProt: O60566