ORC3 Antikörper (AA 325-375)

Produktnummer ABIN7453837

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ORC3 in WB, IP und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ORC3 Antikörper (AA 325-375) (ABIN7453837)

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-ORC3 Antikörper

Bindungsspezifität: AA 325-375

Verwendungszweck: Rabbit anti-ORC3 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 325 and 375

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ORC3

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Andere Bezeichnung: ORC3

Hintergrund: Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC3 is also known as ORC3L and is a subunit of the human ORC complex. ORC3L forms a core complex with ORC2L, -4L, and -5L [taken from NCBI Entrez Gene (GeneID: 23595)].

Gen-ID: 23595

NCBI Accession: NP_036513

UniProt: Q9UBD5

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA