UVRAG Antikörper (AA 649-699)
Kurzübersicht für UVRAG Antikörper (AA 649-699) (ABIN7453808)
Target
Alle UVRAG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 649-699
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Verwendungszweck
- Rabbit anti-UVRAG Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 649 and 699
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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Andere Bezeichnung
- UVRAG
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Hintergrund
- Background: UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.
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Gen-ID
- 7405
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NCBI Accession
- NP_003360
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UniProt
- Q9P2Y5
Target
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