SRPK1 Antikörper (AA 275-325)
Kurzübersicht für SRPK1 Antikörper (AA 275-325) (ABIN7453793)
Target
Alle SRPK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 275-325
-
Verwendungszweck
- Rabbit anti-SRPK1 Antibody, Affinity Purified
-
Homologie
- Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 275 and 325
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- SRPK1 (SRSF Protein Kinase 1 (SRPK1))
-
Andere Bezeichnung
- SRPK1
-
Hintergrund
- Background: Serine/arginine rich protein-specific kinase 1 (SRPK1) plays a central role in the regulatory network for splicing by controlling the intranuclear distribution of splicing factors in interphase cells and the re-organization of nuclear speckles during mitosis. During metaphase, SRPK1 hyperphosphorylates RS domain-containing proteins such as SFRS1 and SFRS2 on serine residues. SRPK1 also appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids [taken from the Universal Protein Resource (UniProt) Q96SB4].
-
Gen-ID
- 6732
-
NCBI Accession
- NP_003128
-
UniProt
- Q96SB4
-
Pathways
- Toll-Like Receptors Cascades
Target
-