OSR1 Antikörper (AA 375-425)
Kurzübersicht für OSR1 Antikörper (AA 375-425) (ABIN7453750)
Target
Alle OSR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 375-425
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Verwendungszweck
- Rabbit anti-OSR1 Antibody, Affinity Purified
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Homologie
- Mouse,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 375 and 425
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- OSR1 (Odd-Skipped Related 1 (OSR1))
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Andere Bezeichnung
- OSR1
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Hintergrund
- Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.
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Gen-ID
- 9943
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NCBI Accession
- NP_005100
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UniProt
- O95747
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Pathways
- Tube Formation
Target
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