FLII Antikörper (AA 425-475)

Produktnummer ABIN7453708

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FLII in WB, IP und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FLII Antikörper (AA 425-475) (ABIN7453708)

Target: FLII (Flightless I Homolog (FLII))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-FLII Antikörper

Bindungsspezifität: AA 425-475

Verwendungszweck: Rabbit anti-Flightless-1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 425 and 475

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu FLII

Target: FLII (Flightless I Homolog (FLII))

Andere Bezeichnung: Flightless-1

Hintergrund: Background: Flightless-1 is the human homolog of the drosophila flightless (fli1), a gene required for proper development of flight muscles and essential to embryonic development. It is a member of the gelsolin family of actin-binding proteins, and is highly conserved among vertebrates and invertebrates. The actin-remodeling activity of flightless-1 may have multiple roles in the cell. Studies in transgenic mice indicate a role in wound healing that may involve the regulation of cell migration and proliferation. Flightless-1 has also been found to be associated with complexes involved in transcriptional regulation. It associates with CARM1, a protein arginine methyltransferase, and may function as a nuclear receptor coactivator via this interaction. It has also been shown to associate with the BAF53a subunit of the SWI/SNF-like chromatin remodeling complexes.

Gen-ID: 2314

NCBI Accession: NP_002009

UniProt: Q13045