Fatty Acid Synthase Antikörper (AA 1175-1225)

Produktnummer ABIN7453706

Der Kaninchen Polyklonal Anti-Fatty Acid Synthase-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet, Fatty Acid Synthase in Proben von Human zu detektieren.

Kurzübersicht für Fatty Acid Synthase Antikörper (AA 1175-1225) (ABIN7453706)

Target: Fatty Acid Synthase (FASN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-Fatty Acid Synthase Antikörper

Bindungsspezifität: AA 1175-1225

Verwendungszweck: Rabbit anti-FASN Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1175 and 1225

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: FASN

Hintergrund: Background: Fatty acid synthase (FASN) is a multifunctional protein that is mainly involved in catalyzing the synthesis of long-chain fatty acids. FASN has recently been viewed as an important protein involved in carcinogenesis as it has been found to be constitutively active in subsets of carcinomas and is associated with a poor prognosis. The inhibition of FASN activity in cancer cells promotes apoptosis and thus may play a role in maintaining cancer cell survival.

Gen-ID: 2194

NCBI Accession: NP_004095

UniProt: P49327

Pathways: AMPK Signaling