CASC3 Antikörper (AA 653-703)
Kurzübersicht für CASC3 Antikörper (AA 653-703) (ABIN7453674)
Target
Alle CASC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 653-703
-
Verwendungszweck
- Rabbit anti-CASC3 Antibody, Affinity Purified
-
Homologie
- Bovine
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 653 and 703
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
-
Andere Bezeichnung
- CASC3
-
Hintergrund
- Background: Cancer susceptibility candidate gene 3 protein (CASC3) is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. CASC3 is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles [taken from NCBI Entrez Gene (GeneID: 22794)].
-
Gen-ID
- 22794
-
NCBI Accession
- NP_031385
-
UniProt
- O15234
Target
-