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Cyclin T1 Antikörper (AA 325-375)

CCNT1 Reaktivität: Human WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7453623
  • Target Alle Cyclin T1 (CCNT1) Antikörper anzeigen
    Cyclin T1 (CCNT1)
    Bindungsspezifität
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-375
    Reaktivität
    • 39
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 34
    • 4
    • 1
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 23
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin T1 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 15
    • 12
    • 10
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-Cyclin T1 Antibody, Affinity Purified
    Homologie
    Chimpanzee
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 325 and 375
    Isotyp
    IgG
    Top Product
    Discover our top product CCNT1 Primärantikörper
  • Applikationshinweise

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    Cyclin T1 (CCNT1)
    Andere Bezeichnung
    Cyclin T1 (CCNT1 Produkte)
    Hintergrund
    Background: Cyclin T1 is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, Cyclin T1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA) [taken from the Universal Protein Resource (UniProt) O60563].
    Gen-ID
    904
    NCBI Accession
    NP_001231
    UniProt
    O60563
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