DDX6 Antikörper (AA 425-483)

Produktnummer ABIN7453597

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DDX6 in WB, IP und IHC (fp). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für DDX6 Antikörper (AA 425-483) (ABIN7453597)

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-DDX6 Antikörper

Bindungsspezifität: AA 425-483

Verwendungszweck: Rabbit anti-DDX6 Antibody, Affinity Purified

Homologie: Guinea pig_10141,Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 425 and 483

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:25,000 - 1:50,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu DDX6

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Andere Bezeichnung: DDX6

Hintergrund: Background: DDX6 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX6 has been observed to positively regulate growth by modulating gene expression at the translational level.

Gen-ID: 1656

NCBI Accession: NP_004388

UniProt: P26196

Pathways: Ribonucleoprotein Complex Subunit Organization